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US HUPO: Introduction to Bottom-Up Proteomics Informatics (2011)

Sunday, March 20, 2011, 9:00 am - 12:00 pm


Nathan Edwards (Georgetown)

Course Description

This class will provide an introduction to the informatics of protein identification from bottom-up/shotgun proteomics workflows. The class is intended for applied laboratory or computational researchers seeking basic, practical instruction in the analysis of peptide tandem mass-spectra datasets. Topics will include: search engines, protein sequence databases, and statistical significance of search results.

Advanced topics, such as proteogenomics, meta-search, and result combining may be covered as time and interest permits. The class will conclude with a hands-on tandem mass-spectrometry analysis exercise on participants' laptop computers.


Hands-on Exercises